Lifecycle
- Obsolete Date 31-07-2025
Specifications
- Processor cache 11 MB L3
- Included memory 32 GB RDIMM
- Processor core available 8 core
- Memory, standard 32 GB (1x 32GB) RDIMM
- Weight 32.6 lb
- Storage controller HPE MR416i-p Gen10 Plus x16 Lanes 4GB Cache NVMe/SAS 12G Controller
- Form factor 2U Rack
- Warranty 3/3/3: Server Warranty includes three years of parts, three years of labor, and three years of onsite support coverage. Additional information regarding worldwide limited warranty and technical support is available at: https://support.hpe.com/hpesc/public/docDisplay?docId=sd00004309en_us. Additional HPE support and service coverage, to supplement the product warranty, is available. For more information, visit https://www.hpe.com/support.
- Product dimensions (imperial) 17.54 x 28.75 x 3.44 in
- Weight 14.76 kg
- NVDIMM capacity Up to 1 TB per processor
- NVDIMM rank Not applicable
- NVDIMM type HPE NVDIMM-N *Only available on 1st Generation Intel® Xeon® Scalable Processors
- Security Optional locking Bezel Kit, Intrusion Detection Kit, and HPE TPM 2.0
- Infrastructure management HPE iLO Standard with Intelligent Provisioning (embedded), HPE OneView Standard (requires download) (standard) HPE iLO Advanced, and HPE OneView Advanced (optional; requires licenses)
- Product dimensions (metric) 44.55 x 73.03 x 8.74 cm
- Processor number 1 processor included
- Processor speed 3.20 GHz
- Processor name Intel® Xeon® Silver 4215R (8 core, 3.20 GHz, 11 MB L3, 130W)
- System fan features 4 single-rotor, standard fans included
- Included drives None ship standard, 8 SFF supported
- Optical drive type Optional
- Power supply type 1x HPE 800W Flex Slot Titanium Hot Plug Low Halogen Power Supply Kit
- Network controller HPE Ethernet 10Gb 2-port 535FLR-T Adapter
- Expansion slots 3 PCIe 3.0, for detailed descriptions reference the QuickSpecs
- Memory type HPE DDR4 Smart Memory
Quickspecs
Overview
Where is your server bottlenecked…storage, compute, expansion? The HPE ProLiant DL380 Gen10 server delivers the latest in security, performance and expandability, backed by a comprehensive warranty. Standardize on the industry's most trusted compute platform. The HPE ProLiant DL380 Gen10 server is securely designed to reduce costs and complexity, featuring the First and Second Generation Intel® Xeon® Processor Scalable Family with up to a 60% performance gain 1 and 27% increase in cores 2, plus the HPE 2933 MT/s DDR4 SmartMemory supporting 3.0 TB. It supports 12 Gb/s SAS, and up to 20 NVMe drive plus a broad range of compute options. Intel® Optane™ persistent memory 100 series for HPE offers unprecedented levels of performance for databases and analytic workloads. Run everything from the most basic to mission-critical applications and deploy with confidence.
What’s new
- Intel® Optane™ persistent memory 100 series for HPE offers the flexibility to deploy as dense memory or fast storage and enables per-socket memory capacity of up to 3.0 TB. 3
- iLO 5 security enhancements: Server Configuration Lock, iLO Security Dashboard and Workload Performance Advisor. HPE InfoSight provides cloud-based analytics to predict and prevent issues proactively.
- Defend applications and data before your server is built with the new HPE Trusted Supply Chain offering.
- Supporting additional second generation Intel® Xeon® Scalable processor family offerings.
- Increased Single-Width GPU Density with up to 7 NVIDIA Tesla T4 16GB Computational Accelerators or 7 Xilinx Alveo U50 Accelerators supported in a standard-depth 2U rack form factor
- Networking Choice (NC) server models provide greater flexibility in the primary networking selection.
Features
Learn more about HPE Trusted Supply Chain
World-Class Performance featuring Enhanced Compute Density
The ProLiant DL380 now features significantly enhanced GPU density, expanding support from five to seven Full-Height, Half-Length, Single-Width Accelerators/GPUs; or up to six in a balanced configuration with additional PCIe expansion via the tertiary riser.
Leveraging HPE's most popular 2U rackmount server, fitting standard depth racks, customers can benefit from one of the densest Accelerator/GPU platforms with an extensive set of Accelerator options, enabling diverse cloud workload performance and optimization of AI and deep learning experiences.
Supported on the ProLiant DL380, the NVIDIA T4 GPU is ideal for Deep learning, Inferencing, Machine Learning, HPC, Rendering, VDI, Virtual Workstations and combinations thereof for mixed workloads – maximizing utilization of data center resources and lowering TCO.
Defend Applications and Data Before Your Server is Built with HPE Trusted Supply Chain
A new first line of defense against cyber-attackers with select servers built to the world’s toughest security standards in secured facilities, bringing together security, processes and people to deliver protection for your most sensitive applications and data even before your server is built.
Built in secure HPE facilities to the most stringent Country of Origin USA and conformance requirements, HPE Trusted Supply Chain servers are inspected to be free from malicious microcode and counterfeit parts, safeguarding it against cyber-exploits throughout its life cycle.
With hardened security built in, HPE Trusted Supply Chain hardens the protections designed into select HPE products with unrivaled supply chain visibility and standards compliance providing a 360-degree view and mitigation plan for current and emerging cyber-threats.
Flexible Design Making Your Investment Expand As Your Business Needs Grow
The HPE ProLiant DL380 Gen10 server has an adaptable chassis, including new Hewlett Packard Enterprise modular drive bay configuration options with up to 30 SFF, up to 19 LFF or up to 20 NVMe drive options along with support for up to three double wide GPU options.
Adapting and growing to changing business needs, Networking Choice (NC) server models provide flexibility in the primary networking choice while Embedded LOM server models offer an embedded 4x1GbE by default; both provide network options (1GbE to 100GbE) via HPE FlexibleLOM or PCIe standup adapters.
HPE Persistent Memory works with DRAM to provide fast, high capacity, cost effective memory and storage to transform big data workloads and analytics by enabling data to be stored, moved, and processed quickly.
In conjunction with the embedded SATA HPE Dynamic Smart Array S100i Controller for boot, data and media needs, the redesigned HPE Smart Array Controllers allow you the flexibility to choose the optimal 12 Gb/s controller most suited to your environment, and operate in both SAS and HBA mode.
Allied to ensure authenticity, HPE Trusted Supply Chain doubles down on your protection with vetted HPE employees assigned to the product build to manage the product manufacturing process that adheres to the strictest sourcing, inspection and traceability standards.
Supporting a wide range of operating environments from Azure to Docker to ClearOS in addition to traditional operating systems.
The HPE ProLiant DL380 Gen10 server comes with a complete set of HPE Technology Services, delivering confidence, reducing risk, and helping customers realize agility and stability.
HPE Services simplifies all stages of the IT journey. Advisory and Transformation Services professionals understand customer challenges and design an optimal solution. Professional Services enable rapid deployment of solutions and Operational Services provide ongoing support.
Industry Leading Services and Ease of Deployment
A suite of embedded and downloadable tools is available for server lifecycle management including Unified Extensible Firmware Interface (UEFI), Intelligent Provisioning; HPE iLO 5 to monitor and manage; Smart Update Manager (SUM), and Service Pack for ProLiant (SPP).
Hewlett Packard Enterprise IT investment solutions help you transform to a digital business with IT economics that align to your business goals.
Media
【第1回】HPE ProLiant DL380 Gen10 サーバーユーザーガイドを解説します ~外部コンポーネント編~
HPE ProLiant DL380 Gen10 サーバーユーザーガイドの内容に沿って、実機を触りながら解説します。
Panorama do produto HPE ProLiant DL380
Este vídeo destaca os principais recursos e benefícios de hardware do servidor HPE ProLiant DL380 Gen10.
HPE ProLiant DL380 제품 살펴보기
이 비디오는 HPE ProLiant DL380 Gen10 서버의 주요 하드웨어 기능과 이점에 대해 집중 조명합니다.
HPE ProLiant DL380 Gen10 Server – Hardware Tour
HPE ProLiant DL380 Gen10 Server – Hardware Tour.
Présentation du produit HPE ProLiant DL380
Cette vidéo présente les principales caractéristiques matérielles et les avantages du serveur HPE ProLiant DL380 Gen10.
HPE ProLiant DL380 Produkttour
In diesem Video werden die wichtigsten Hardwarefunktionen und Vorteile des HPE ProLiant DL380 Gen10 Servers vorgestellt.
Presentazione del prodotto HPE ProLiant DL380
Questo video illustra le principali caratteristiche hardware e i vantaggi offerti dal server HPE ProLiant DL380 Gen10.
Presentación del producto HPE ProLiant DL380
Este vídeo destaca las características y ventajas clave de hardware del servidor HPE ProLiant DL380 Gen10.
Сервер HPE ProLiant DL385 Gen10 — обзор продукта
В данном видео представлены ключевые характеристики и преимущества сервера HPE ProLiant DL380 Gen10.
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Documents
- HPE ProLiant DL380 Gen10 Carrier Grade Server QuickSpecs
- HPE Reference Architecture for SAP HANA System Replication on HPE Superdome Flex 280 Server (Scale-Up Configuration Built with Intel Cooper Lake)
- Rising to the streaming challenge – D’LIVE companion slide
- HPE Reference Architecture for backup and recovery of SAP HANA database on HPE Superdome Flex 280 server (Scale-up configuration built with Intel Cooper Lake)
- HPE Reference Configuration for Hortonworks Data Platform on HPE Elastic Platform for Big Data Analytics (EPA)
- Bringing certainty to healthcare’s digital journey – Slovenj Gradec General Hospital digital game changers one-page overview
- HPE Reference Configuration for MapR on HPE Elastic Platform for Big Data Analytics (EPA)
- HPE Reference Configuration for Cloudera Enterprise on HPE Elastic Platform for Big Data Analytics (EPA)
- HPE Solutions with Aerospike configuration guide
- HPE ConvergedSystem 300 for Microsoft Analytics Platform: Data Integration Platform – HPE ProLiant DL380 Gen10 reference guide
- More agility and speed with SAP S/4HANA– Amico Group
- Fogsphere transforms workplace safety with AI and HPE technology
- HPE ProLiant Compute DL380a Gen12
- Verified Reference Configuration – Intel-HPE VRC for NFVI and SASE
- Moving the world safely – Wabtec Corporation companion slide
- Moving the world safely – Wabtec Corporation case study
- Modernizing payment systems for the future of cashless payments – Sumitomo Mitsui Card digital game changers one-page overview
- Strengthening Ecuador’s defense by securing data – Fuerza Aérea Ecuatoriana
- Service-driven model for optimal infrastructure investment – QUALICA
- Bringing certainty to healthcare’s digital journey – Slovenj Gradec General Hospital companion slide
- HPE Reference Configuration for Red Hat OpenShift Virtualization on HPE ProLiant DL360 and DL380 Gen11 servers using Red Hat OpenShift Container Platform 4.15
- Rising to the streaming challenge – D’LIVE digital game changers one-page overview
- Engineering at a totally new level – Heson success slide
- More speed for Speedition – Tirolia Spedition success slide
- Transforming video production with advanced technology – Avid Technology, Inc.
- Accelerate performance on Apache Hadoop workloads with Intel Optane DC SSDs and HPE ProLiant DL380 Gen10 servers
- HPE Reference Configuration for Citrix VDI on HPE ProLiant Servers
- Fast, secure access from anywhere – HPE SMB Solutions for Remote Workers
- HPE Firmware and Software Compatibility Matrix for VMware Cloud Foundation 4.3.1 on HPE Synergy and HPE ProLiant Servers Oct2021
- HPE ProLiant DL380 Gen10 Server QuickSpecs
- 10 reasons HPE Compute helps accelerate your IT modernization
- Data protection with HPE StoreOnce Catalyst and Commvault
- HPE Reference Architecture for HPE StoreOnce VSA and VMware vSphere High Availability
- Meet diverse needs with efficiency
- Ready to deploy HPE remote user compute solutions brochure
- HPE Reference Configuration for Enterprise AI Infrastructure on HPE ProLiant DL380 Gen10 Server
- Securing the Evolved Hybrid Business Impact Brief
- Microsoft SQL Server 2022 on HPE MSA Gen6 Storage
- First-class infrastructure for a cloud-first strategy – Finmatica
- HPE Reference Architecture for Remote Artist Workstations with Avid, Teradici, and NVIDIA on HPE ProLiant DL380 Server
- HPE OEM program helps OmniPlayer speed delivery of mission-critical broadcast solutions companion slide
- Building in Infrastructure Trust Business Impact Brief
- HPE Reference Architecture for Microsoft SQL Server 2017 on HPE SimpliVity 380
- Cost-Effective Virtualized OLTP SQL Server Performance with HPE Persistent Memory
- HPE and Commvault – HPE ProLiant for Microsoft Azure Stack and Commvault Complete Backup and Recovery product brochure
- Upgrading VMware Cloud Foundation from 4.2.1 to 4.3.1 on HPE Servers
- Next-Gen Data Backup Drives Secure, Scalable, Manageable IT
- Iceotope Develops Innovative Cooling Systems for Extreme Environments
- Perimeter security goes digital – Heras companion slide
- HPE Reference Architecture for VMware Cloud Foundation 4.4 on HPE ProLiant DL Servers
- HPE Reference Configuration for Deploying Microsoft SQL Server on Red Hat OpenShift Container Platform on HPE ProLiant DL360 and DL380 Gen10 with HPE Primera A650 Storage
- Solving Uruguay’s biggest challenges – Universidad de la República Uruguay companion slide
- Solving Uruguay’s biggest challenges – Universidad de la República Uruguay digital game changers one-page overview
- AI-Powered Computer Vision for the New Wave of Retail solution brief
- Outsmarting cybercriminals with stealth – Datex companion slide
- Outsmarting cybercriminals with stealth – Datex digital game changers one-page overview
- Embrace the change: Creating flexible, scalable infrastructure to comply with Italy’s cloud-first strategy
- Upending the Latin America market with scalable cloud services – DataCloud
- HPE Reference Architecture for VMware Cloud Foundation 4.3.1 on HPE ProLiant as Management and HPE Synergy as Workload Domains
- Self-service drives clients’ transformation plans – COMLINE companion slide
- Building trust and value with hybrid cloud – Co-operative Group
- Building trust and value with hybrid cloud – Co-operative Group
- HPE and F5 – HPE ProLiant and F5 BIG-IP ADC and F5 Distributed Cloud Platform
- BWI Group's Digital transformation yields satisfaction and long-term reliability – BWI Group companion slide
- HPE Reference Architecture for VMware Cloud Foundation 4.5 on HPE ProLiant DL325 Gen10 Plus as Management Domain and HPE ProLiant DL380 Gen10 Plus as Workload Domain
- Perimeter security goes digital – Heras digital game changers one-page overview
- HPE and Global Financial Services Provider solution overview
- HPE OEM program and MWI mobile wireless communication technologies – Metropolitan Wireless International
- Perimeter security goes digital – Heras case study
- Expanding patient services, reducing wait times – PrairieStar Health Center
- Expanding patient services, reducing wait times – PrairieStar Health Center
- Expanding patient services, reducing wait times – PrairieStar Health Center
- Desktop Virtualization Solutions to rapidly unleash the productivity of your remote workforce
- Self-service drives clients’ transformation plans – COMLINE case study
- Bringing certainty to healthcare’s digital journey – Slovenj Gradec General Hospital
- Vital Images helps support better patient outcomes with data-driven diagnostics and analytics case study
- Traditionally Innovative – RIEDER Zillertal case study
- HPE Server Performance Benchmarks Newsletter
- From dated data centers to future-ready solutions – KBTG
- HPE and Bloombase – HPE ProLiant and Bloombase StoreSafe Intelligent Storage Firewall
- Modernizing payment systems for the future of cashless payments – Sumitomo Mitsui Card companion slide
- Hermes Medical Solutions changes lives with innovative molecular imaging – Hermes Medical Solutions
- Elevating wireless connectivity to new heights with AI
- Self-service drives clients’ transformation plans – COMLINE digital game changers one-page overview
1 HPE measurements: Up to 60% performance increase of Intel Xeon Platinum vs. previous generation E5-2600 v4 average gains of STREAM, LINPACK, SPEC CPU 2006 & SPEC CPU2017 metrics on HPE servers comparing 2-socket Intel Xeon Platinum 8280 to E5-2699 v4 family processors. Any difference in system hardware or software design or configuration may affect actual performance. April 2019.
2 Up to 27% cores increase of Intel Xeon Platinum vs. previous generation comparing 2-socket Intel Xeon Platinum 8280 (28 cores) to E5-2699 v4 (22 cores). Calculation 28 cores/22 cores= 1.27 = 27%. April 2019.
3 3.0 TB per socket with 512GB 2666 Persistent Memory Kit





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