HPE ProLiant DL380 Gen10 Plus 4310 12c 1P 2x32GB-R SR416i-a 2x480GB SATA SSD 2x800W PS EU Server (P80569-425)

Lifecycle

• Obsolete Date 10-07-2025

Specifications

• Expansion slots 8, for detailed descriptions refer to the QuickSpecs
• Memory type HPE DDR4 Smart Memory
• Processor core available 12 core
• Processor number 1 processor included
• Warranty 3/3/3: Server Warranty includes three years of parts, three years of labor, and three years of onsite support coverage. Additional information regarding worldwide limited warranty and technical support is available at: https://support.hpe.com/hpesc/public/docDisplay?docId=sd00004309en_us. Additional HPE support and service coverage, to supplement the product warranty, is available. For more information, visit https://www.hpe.com/support.
• Power supply type 2x HPE 800W Flex Slot Titanium Hot Plug Low Halogen Power Supply Kit
• Network controller Broadcom BCM5719 Ethernet 1Gb 4-port BASE-T OCP3 Adapter for HPE
• NVDIMM capacity Optional: 128 GB – 512 GB
• NVDIMM type Optional: Intel® Optane™ Persistent Memory for HPE
• Security Optional locking Bezel Kit, Intrusion Detection Kit, and HPE TPM 2.0
• Infrastructure management HPE iLO Standard with intelligent provisioning (embedded), HPE OneView Standard (requires download) (standard) HPE iLO Advanced, and HPE OneView Advanced (optional, requires licenses)
• Storage controller HPE SR416i-a Gen10 Plus x16 Lanes 4GB Cache NVMe/SAS 24G Controller
• Optical drive type Optional DVD-ROM Optional via Universal Media Bay External support only
• Form factor 2U Rack
• Processor speed 2.10 GHz
• System fan features 6x Maximum Performance Fans
• Processor name Intel® Xeon® Silver 4310 (12 core, 2.10 GHz, 18 MB L3, 120W)
• Processor cache 18 MB L3
• Accelerators Optional
• Included memory 64 GB (2×32 GB, 3200 MT/s)
• Included drives 2x HPE 480GB SATA 6G Read Intensive SFF BC Multi Vendor SSD

Quickspecs

• QuickSpecs
• QuickSpecs (PDF)
• QuickSpecs
• QuickSpecs (HTML)

Overview

Do your servers need increased performance in storage, compute, or expansion? The HPE ProLiant DL380 Gen10 Plus server is adaptable for diverse workloads and environments, providing you with the right balance of expandability and scalability. Designed for supreme versatility and resiliency, this 2U/2P platform is capable for deployment in multiple environments, built on 3rd Generation Intel® Xeon® Scalable Processors, and backed by a comprehensive warranty. Equipped with PCIe Gen4 capabilities, the HPE ProLiant DL380 Gen10 Plus server offers improved data transfer rates and higher networking speeds.

What’s new

• Supports 3rd Generation Intel® Xeon® Scalable Processors.
• Support for PCIe Gen4, resulting in improved bandwidth and throughput.
• Support for industry-standard OCP 3.0 Network Adapters.
• Support for Trimodal (NVMe/SAS/SATA) HPE Smart Array controllers.

Features

HPE ProLiant servers provide rapid detection of a security-compromised server, even to the point of not allowing it to boot, verify containment of malicious code, and protect healthy servers.

HPE ProLiant servers provide automated recovery from a security event, including restoration of validated firmware, and facilitating recovery of operating system, application and data connections, providing the fastest path to bring a server back online and into normal operations.

When it’s time to retire or repurpose an HPE ProLiant server, one button secure erase speeds and simplifies the complete removal of passwords, configuration settings and data, preventing inadvertent access to previously secured information.

The HPE ProLiant DL380 Gen10 Plus server is built with foundational intelligence to transform IT with insights that enhance workload performance, placement, and efficiency, delivering better outcomes faster.

Provide real-time operational feedback on server performance and recommendations for fine-tuning BIOS settings to customize for changing business needs.

360-degree Holistic Security

The HPE ProLiant DL380 Gen10 Plus server provides an enhanced, holistic, 360-degree view to security that begins in the manufacturing supply chain and concludes with a safeguarded, end-of-life decommissioning.

HPE ProLiant security begins with the corruption-free manufacture of the server and auditing the integrity of every component – hardware and firmware – to provide verification that the server begins its lifecycle uncompromised through the supply chain.

Built for Some of the Most Demanding Workloads

Automation and software defined control reduces time spent on provisioning and maintenance, as well as reduces deployment times from weeks to mere days.

Available in an As-a-Service Experience

The HPE ProLiant DL380 Gen10 Plus server is supported by HPE GreenLake to simplify IT infrastructure management across your entire hybrid estate. With 24×7 monitoring and management, our experts do the heavy lifting to manage your environment with services built into consumption-based solutions.

Hewlett Packard Enterprise provides customers choice in how they acquire and consume IT beyond traditional financing and leasing, offering options that free trapped capital, accelerate infrastructure updates, and provide on-premises pay-per-use consumption with HPE GreenLake.

Intelligent Management Automation

The HPE ProLiant DL380 Gen10 Plus server simplifies and automates management tasks, establishing a solid foundation for an open, hybrid cloud platform enabled by composability.

Embedded in HPE servers, HPE Integrated Lights-Out (iLO) is an exclusive core intelligence that monitors server status, providing the means for reporting, ongoing management, service alerting, and local or remote management to quickly identify and resolve issues.

Media

HPE ProLiant DL380 Gen10 Plus Product Overview

HPE ProLiant servers deliver the intelligent compute foundation for the hybrid cloud delivering unmatched workload optimization, 360-degree security, and intelligent automation, all available with an as-a-Service experience.

Compatible products

• HPE iLO Advanced 1-server License with 1yr Support on iLO Licensed Features
• HPE Small Form Factor Hard Drive Blank Kit
• HPE Mobile USB DVD-RW Optical Drive
• HPE 9.5mm SATA DVD-ROM Jb Gen9 Kit
• HPE 9.5mm SATA DVD-RW Optical Drive
• HPE DL380 SFF Smart Array HBA H200/P400 Series SAS Cable Kit
• HPE Smart Array E208i-a SR Gen10 Ctrlr
• HPE Smart Array P408i-a SR Gen10 (8 Internal Lanes/2GB Cache) 12G SAS Modular Controller
• HPE Smart Array P816i-a SR Gen10 (16 Internal Lanes/4GB Cache/SmartCache) 12G SAS Modular Controller
• HPE Smart Array E208i-p SR Gen10 (8 Internal Lanes/No Cache) 12G SAS PCIe Plug-in Controller
• HPE Smart Array E208e-p SR Gen10 (8 External Lanes/No Cache) 12G SAS PCIe Plug-in Controller
• HPE Smart Array P408e-p SR Gen10 (8 External Lanes/4GB Cache) 12G SAS PCIe Plug-in Controller
• HPE Gen9 LFF HDD Spade Blank Kit
• HPE Smart Array P408i-p SR Gen10 (8 Internal Lanes/2GB Cache) 12G SAS PCIe Plug-in Controller
• HPE 2TB SAS 12G Business Critical 7.2K LFF LP 1-year Warranty Multi Vendor HDD
• HPE 4TB SAS 12G Business Critical 7.2K LFF LP 1-year Warranty Multi Vendor HDD
• HPE 8TB SATA 6G Business Critical 7.2K LFF LP 1-year Warranty 512e Multi Vendor HDD
• HPE 6TB SATA 6G Business Critical 7.2K LFF LP 1-year Warranty 512e Multi Vendor HDD
• HPE 6TB SAS 12G Business Critical 7.2K LFF LP 1-year Warranty 512e Multi Vendor HDD
• HPE 800W Flex Slot -48VDC Hot Plug Low Halogen Power Supply Kit
• HPE 800W Flex Slot Titanium Hot Plug Low Halogen Power Supply Kit
• HPE Gen10 2U Bezel Kit
• HPE Bezel Lock Kit
• HPE 12TB SAS 12G Business Critical 7.2K LFF LP 1-year Warranty Helium 512e Multi Vendor HDD
• HPE 12TB SATA 6G Business Critical 7.2K LFF LP 1-year Warranty Helium 512e Multi Vendor HDD
• HPE C13 – C14 WW 250V 10Amp 2.0m Jumper Cord
• HPE iLO Advanced 1-server License with 3yr Support on iLO Licensed Features
• HP OV 3yr 24×7 Supp Flex E-LTU
• HPE OV for DL 3y 24×7 Bdl Track 1Svr Lic
• HPE iLO Advanced Electronic License with 1yr Support on iLO Licensed Features
• HPE iLO Advanced Electronic License with 3yr Support on iLO Licensed Features
• HPE 3 Year Tech Care Basic DL380 Gen10/Gen10+ Smart Choice Service
• HPE 3 Year Tech Care Essential DL380 Gen10/Gen10+ Smart Choice Service
• HPE 5 Year Tech Care Basic DL380 Gen10/Gen10+ Smart Choice Service
• HPE 5 Year Tech Care Essential DL380 Gen10/Gen10+ Smart Choice Service
• HPE 96W Smart Storage Lithium-ion Battery with 145mm Cable Kit
• HPE Smart Storage Hybrid Capacitor with 145mm Cable Kit
• HPE 1000W Flex Slot Titanium Hot Plug Power Supply Kit
• HPE 16GB (1x16GB) Dual Rank x8 DDR4-3200 CAS-22-22-22 Registered Smart Memory Kit
• HPE 32GB (1x32GB) Dual Rank x4 DDR4-3200 CAS-22-22-22 Registered Smart Memory Kit
• HPE 64GB 2Rx4 PC4-3200AA-R Smart Kit
• HPE MR416i-p Gen10 Plus x16 Lanes 4GB Cache NVMe/SAS 12G Controller
• HPE 8GB (1x8GB) Single Rank x8 DDR4-3200 CAS-22-22-22 Registered Smart Memory Kit
• HPE DDR4 DIMM Blank Kit
• Intel I350-T4 Ethernet 1Gb 4-port BASE-T OCP3 Adapter for HPE
• Broadcom BCM57416 Ethernet 10Gb 2-port BASE-T OCP3 Adapter for HPE
• Mellanox MCX562A-ACAI Ethernet 10/25Gb 2-port SFP28 OCP3 Adapter for HPE
• HPE NS204i-p x2 Lanes NVMe PCIe3 x8 OS Boot Device
• Mellanox MCX512F-ACHT Ethernet 10/25Gb 2-port SFP28 Adapter for HPE
• HPE Trusted Platform Module 2.0 Gen10 Plus Black Rivets Kit
• HPE DL38X Gen10 Plus Primary NEBS-compliant Riser Kit
• HPE DL38X Gen10 Plus Tertiary NEBS-compliant Riser Kit
• HPE DL38X Gen10+ 2LFF Prim FIO Kit
• HPE DL38X Gen10+ 2LFF Tertiary FIO Kit
• HPE DL38X Gen10 Plus x8/x8 Tertiary Riser Kit
• HPE DL38X Gen10 Plus x8/x16/x8 Secondary Riser Kit
• HPE DL38X Gen10 Plus x16 Tertiary Riser Kit
• HPE DL38X Gen10 Plus x16/x16 Slot 1/2 Secondary Riser Kit
• HPE DL38X Gen10 Plus x16/x16 Slot 2/3 Secondary Riser Kit
• HPE DL38X Gen10 Plus Slot1 x16 Adder for Slot2/3 Riser Kit
• HPE DL38X Gen10 Plus AROC to NVMe Adapter Kit
• HPE Gen10 Plus Chassis Intrusion Detection Kit
• HPE DL38X Gen10 Plus Maximum Performance Fan Kit
• HPE DL38X Gen10 Plus Universal Media Bay Kit
• Intel I350-T4 Ethernet 1Gb 4-port BASE-T Adapter for HPE
• Xilinx X2522-25G-PLUS Ethernet 10/25Gb 2-port SFP28 Adapter for HPE
• HPE 32GB microSD RAID 1 USB Boot Drive
• HPE DL38X Gen10 Plus 2U SFF Easy Install Rail Kit
• HPE DL38X Gen10 Plus 2U LFF Easy Install Rail Kit
• HPE DL38X Gen10 Plus 2U Cable Management Arm for Rail Kit
• HPE DL38X Gen10 Plus 8NVMe CPU1/2 Cable Kit
• HPE 16TB SATA 6G Business Critical 7.2K LFF LP 1-year Warranty Helium 512e ISE Multi Vendor HDD
• HPE 16TB SAS 12G Business Critical 7.2K LFF LP 1-year Warranty Helium 512e ISE Multi Vendor HDD
• HPE InfiniBand HDR100/Ethernet 100Gb 2-port QSFP56 PCIe4 x16 MCX653106A-ECAT Adapter
• Broadcom BCM57416 Ethernet 10Gb 2-port BASE-T Adapter for HPE
• BCM 57412 10GBE 2P SFP+ OCP3 ADPTR
• Broadcom BCM57412 Ethernet 10Gb 2-port SFP+ Adapter for HPE
• BCM 57414 10/25GbE 2p SFP28 Adptr
• Broadcom BCM57504 Ethernet 10/25Gb 4-port SFP28 Adapter for HPE
• HPE MR416i-a Gen10 Plus x16 Lanes 4GB Cache NVMe/SAS 12G Controller
• HPE ProLiant DL36X Gen10 Plus High Performance Fan Kit
• Pensando Distributed Services Platform DSC-25 Enterprise 10/25Gb 2-port SFP28 Card
• HPE ProLiant DL380 Gen10 Plus High Performance Heat Sink Kit
• HPE DL300 GEN10+ 2U 8SFF X1TMODE U.3 KIT
• HPE 2.4TB SAS 12G Mission Critical 10K SFF BC 3-year Warranty 512e Multi Vendor HDD
• HPE 1.2TB SAS 12G Mission Critical 10K SFF BC 3-year Warranty Multi Vendor HDD
• INT X710 10Gb 2p SFP+ Adptr
• HPE ProLiant DL380 Gen10 Plus Standard Heat Sink Kit
• HPE ProLiant DL300 Gen10 Plus 2U Standard Fan Kit
• HPE 800W Flex Slot Platinum Hot Plug Low Halogen Power Supply Kit
• HPE 1600W Flex Slot Platinum Hot Plug Low Halogen Power Supply Kit
• HPE 300GB SAS 12G Mission Critical 10K SFF BC 3-year Warranty Multi Vendor HDD
• HPE 900GB SAS 12G Mission Critical 15K SFF BC 3-year Warranty Multi Vendor HDD
• HPE 240GB SATA 6G Read Intensive SFF BC Multi Vendor SSD
• HPE 480GB SATA 6G Read Intensive SFF BC Multi Vendor SSD
• HPE 960GB SATA 6G Read Intensive SFF BC Multi Vendor SSD
• HPE 1.92TB SATA 6G Read Intensive SFF BC Multi Vendor SSD
• HPE 3.84TB SATA 6G Read Intensive SFF BC Multi Vendor SSD
• HPE 7.68TB SATA RI SFF BC MV SSD
• HPE 480GB SATA 6G Mixed Use SFF BC Multi Vendor SSD
• HPE 960GB SATA 6G Mixed Use SFF BC Multi Vendor SSD
• HPE 1.92TB SATA 6G Mixed Use SFF BC Multi Vendor SSD
• HPE 3.84TB SAS RI SFF BC VS MV SSD
• HPE 7.68TB SAS 12G Read Intensive SFF BC Value SAS Multi Vendor SSD
• HPE 960GB SAS 12G Mixed Use SFF BC Value SAS Multi Vendor SSD
• MLX MCX631102 10/25GBE 2P SFP28 ADPTR
• HPE 1800W-2200W FS Ti Ht Plg PS Kit
• HPE 960GB SATA 6G Read Intensive LFF LPC Multi Vendor SSD
• HPE 3.2TB SAS 24G Mixed Use SFF BC Multi Vendor SSD
• HPE 1.92TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 PM1733a SSD
• HPE 1.6TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 PM1735a SSD
• HPE 3.2TB NVME MU SFF BC U.3 PM1735A SSD
• Broadcom BCM5719 Ethernet 1Gb 4-port BASE-T Adapter for HPE
• Broadcom BCM5719 Ethernet 1Gb 4-port BASE-T OCP3 Adapter for HPE
• HPE 20TB SATA 7.2K LFF LP ISE MV HDD
• HPE 600GB SAS 10K SFF BC MV HDD
• HPE 1.8TB SAS 10K SFF BC 512E MV HDD
• HPE ProLiant DL38x 8SFF SAS/SATA Tri-Mode Cable Kit
• HPE ProLiant DL38x Gen10 Plus 8SFF SAS/SATA to Tri-Mode Controller Backplane Kit
• HPE ProLiant DL38x Gen10 Plus 4LFF SAS/SATA Tri-Mode Cable Kit
• HPE ProLiant DL38x LFF SAS/SATA Tri-Mode Cable Kit
• HPE 1.92TB NVMe RI SFF BC U.3 CM7 SSD
• HPE 1.92T NVMERI SFF BC U.3ST V2 MV SSD
• HPE 7.68T NVMERI SFF BC U.3ST V2 MV SSD
• HPE SN1100Q 16Gb Single Port Fibre Channel Host Bus Adapter
• HPE SN1100Q 16Gb Dual Port Fibre Channel Host Bus Adapter
• HPE SN1200E 16Gb Single Port Fibre Channel Host Bus Adapter
• HPE SN1200E 16Gb Dual Port Fibre Channel Host Bus Adapter
• HPE SN1610Q 32Gb 1-port Fibre Channel Host Bus Adapter
• HPE SN1610Q 32Gb 2-port Fibre Channel Host Bus Adapter
• HPE SN1610E 32GB 2P FC HBA
• HPE Proliant DL/ML Install Service
• HPE Proliant DL/ML Startup Service

Documents

• HPE ProLiant DL380 Gen10 Plus – Carrier Grade Supplement QuickSpecs
• HPE and Bloombase – HPE ProLiant and Bloombase StoreSafe Intelligent Storage Firewall
• Upgrading VMware Cloud Foundation from 4.0.1 to 4.2.1 on HPE Servers
• Verified Reference Configuration – Intel-HPE VRC for NFVI and SASE
• HPE ProLiant Compute DL380a Gen12
• Expanding patient services, reducing wait times – PrairieStar Health Center
• Expanding patient services, reducing wait times – PrairieStar Health Center
• HPE ProLiant DL380 Gen10 Plus Server QuickSpecs
• HPE and F5 – HPE ProLiant and F5 BIG-IP ADC and F5 Distributed Cloud Platform
• Next-Gen Data Backup Drives Secure, Scalable, Manageable IT
• Iceotope Develops Innovative Cooling Systems for Extreme Environments
• HPE Reference Configuration for Red Hat OpenShift Virtualization on HPE ProLiant DL360 and DL380 Gen11 servers using Red Hat OpenShift Container Platform 4.15
• HPE ProLiant DL360 Gen10 Plus and HPE ProLiant DL380 Gen10 Plus Servers Building Blocks for SAP Implementation
• HPE Firmware and Software Compatibility Matrix for VMware Cloud Foundation 4.3.1 on HPE Synergy and HPE ProLiant Servers Dec2021
• Expanding patient services, reducing wait times – PrairieStar Health Center
• How To Choose The Right AI Tools To Create Value