Lifecycle
- Obsolete Date 10-07-2025
Specifications
- NVDIMM capacity Optional: 128 GB – 512 GB
- NVDIMM type Optional – Intel® Optane™ Persistent Memory 200 Series for HPE
- Weight 63.43 lbs. maximum
- Product dimensions (imperial) 3.44 x 17.54 x 28 in
- Processor cache 24 MB L3
- Product dimensions (metric) 8.75 x 44.54 x 71. cm
- Weight 28.77 kg maximum
- System fan features 6x Maximum Performance Fans
- Included memory 32 GB (1×32 GB, 3200 MT/s)
- Accelerators Optional
- Power supply type 1x HPE 800W Flex Slot Titanium Hot Plug Low Halogen Power Supply Kit
- Expansion slots 8, for detailed descriptions refer to the QuickSpecs
- Infrastructure management HPE iLO Standard with intelligent provisioning (embedded), HPE OneView Standard (requires download) (standard) HPE iLO Advanced, and HPE OneView Advanced (optional, requires licenses)
- Network controller Broadcom BCM57412 Ethernet 10Gb 2-port SFP+ OCP3 Adapter for HPE
- Storage controller HPE MR416i-p Gen10 Plus x16 Lanes 4GB Cache NVMe/SAS 12G Controller
- Optical drive type Optional DVD-ROM Optional via Universal Media Bay External support only
- Memory type HPE DDR4 Smart Memory
- Processor core available 16 core
- Processor name Intel® Xeon® Silver 4314 (16 core, 2.40 GHz, 24 MB L3, 135W)
- Processor number 1 processor included
- Security Optional locking Bezel Kit, Intrusion Detection Kit, and HPE TPM 2.0
- Form factor 2U Rack
- Processor speed 2.40 GHz
- Warranty 3/3/3: Server Warranty includes three years of parts, three years of labor, and three years of onsite support coverage. Additional information regarding worldwide limited warranty and technical support is available at: https://support.hpe.com/hpesc/public/docDisplay?docId=sd00004309en_us. Additional HPE support and service coverage, to supplement the product warranty, is available. For more information, visit https://www.hpe.com/support.
Quickspecs
Overview
Do your servers need increased performance in storage, compute, or expansion? The HPE ProLiant DL380 Gen10 Plus server is adaptable for diverse workloads and environments, providing you with the right balance of expandability and scalability. Designed for supreme versatility and resiliency, this 2U/2P platform is capable for deployment in multiple environments, built on 3rd Generation Intel® Xeon® Scalable Processors, and backed by a comprehensive warranty. Equipped with PCIe Gen4 capabilities, the HPE ProLiant DL380 Gen10 Plus server offers improved data transfer rates and higher networking speeds.
What’s new
- Support for industry-standard OCP 3.0 Network Adapters.
- Support for PCIe Gen4, resulting in improved bandwidth and throughput.
- Support for Trimodal (NVMe/SAS/SATA) HPE Smart Array controllers.
- Supports 3rd Generation Intel® Xeon® Scalable Processors.
Features
HPE ProLiant servers provide rapid detection of a security-compromised server, even to the point of not allowing it to boot, verify containment of malicious code, and protect healthy servers.
The HPE ProLiant DL380 Gen10 Plus server provides an enhanced, holistic, 360-degree view to security that begins in the manufacturing supply chain and concludes with a safeguarded, end-of-life decommissioning.
HPE ProLiant security begins with the corruption-free manufacture of the server and auditing the integrity of every component – hardware and firmware – to provide verification that the server begins its lifecycle uncompromised through the supply chain.
HPE ProLiant servers provide automated recovery from a security event, including restoration of validated firmware, and facilitating recovery of operating system, application and data connections, providing the fastest path to bring a server back online and into normal operations.
When it’s time to retire or repurpose an HPE ProLiant server, one button secure erase speeds and simplifies the complete removal of passwords, configuration settings and data, preventing inadvertent access to previously secured information.
Built for Some of the Most Demanding Workloads
The HPE ProLiant DL380 Gen10 Plus server simplifies and automates management tasks, establishing a solid foundation for an open, hybrid cloud platform enabled by composability.
The HPE ProLiant DL380 Gen10 Plus server is built with foundational intelligence to transform IT with insights that enhance workload performance, placement, and efficiency, delivering better outcomes faster.
Intelligent Management Automation
Available in an As-a-Service Experience
Embedded in HPE servers, HPE Integrated Lights-Out (iLO) is an exclusive core intelligence that monitors server status, providing the means for reporting, ongoing management, service alerting, and local or remote management to quickly identify and resolve issues.
Automation and software defined control reduces time spent on provisioning and maintenance, as well as reduces deployment times from weeks to mere days.
360-degree Holistic Security
Provide real-time operational feedback on server performance and recommendations for fine-tuning BIOS settings to customize for changing business needs.
The HPE ProLiant DL380 Gen10 Plus server is supported by HPE GreenLake to simplify IT infrastructure management across your entire hybrid estate. With 24×7 monitoring and management, our experts do the heavy lifting to manage your environment with services built into consumption-based solutions.
Hewlett Packard Enterprise provides customers choice in how they acquire and consume IT beyond traditional financing and leasing, offering options that free trapped capital, accelerate infrastructure updates, and provide on-premises pay-per-use consumption with HPE GreenLake.
Media
HPE ProLiant DL380 Gen10 Plus Product Overview
HPE ProLiant servers deliver the intelligent compute foundation for the hybrid cloud delivering unmatched workload optimization, 360-degree security, and intelligent automation, all available with an as-a-Service experience.
Secure Servers with Server Configuration Lock- HPE Gen10 and Gen10 Plus Servers
Supply chain security is an immense and dynamic threat that’s top of mind for enterprise customers. Learn about enabling HPE Server Configuration Lock, an innovative security solution that protects the server configuration against tampering, and the ability to detect and address possible security vulnerabilities.
Compatible products
- HPE 2.4TB SAS 12G Mission Critical 10K SFF BC 3-year Warranty 512e Multi Vendor HDD
- HPE 800W Flex Slot Platinum Hot Plug Low Halogen Power Supply Kit
- HPE 300GB SAS 12G Mission Critical 10K SFF BC 3-year Warranty Multi Vendor HDD
- Xilinx X2522-25G-PLUS Ethernet 10/25Gb 2-port SFP28 Adapter for HPE
- HPE DL38X Gen10 Plus x8/x16/x8 Secondary Riser Kit
- Red Hat Resilient Storage 2 Sockets or 2 Guests 1 Year Subscription E-LTU
- HPE MR416i-p Gen10 Plus x16 Lanes 4GB Cache NVMe/SAS 12G Controller
- HPE 1800W-2200W FS Ti Ht Plg PS Kit
- HPE 3.2TB NVME MU SFF BC U.3 PM1735A SSD
- HPE 3.2TB SAS 24G Mixed Use SFF BC Multi Vendor SSD
- HPE 8GB (1x8GB) Single Rank x8 DDR4-3200 CAS-22-22-22 Registered Smart Memory Kit
- HPE Smart Array P816i-a SR Gen10 (16 Internal Lanes/4GB Cache/SmartCache) 12G SAS Modular Controller
- MS WS25 16C Std ROK EU SW
- Red Hat Enterprise Linux for SAP for Virtual Datacenters 5yr Subscription 24×7 Support E-LTU
- MS WS25 50Usr CAL WW LTU
- MS WS25 16C Std Add Lic WW SW
- HPE 3 Year Tech Care Basic Proliant DL380 Gen10+ Service
- Mellanox MCX512F-ACHT Ethernet 10/25Gb 2-port SFP28 Adapter for HPE
- RHEL Svr 2 Sckt 4 Gst 5yr 24×7 E-LTU
- Marvell QL41132HQCU Ethernet 10Gb 2-port SFP+ OCP3 Adapter for HPE
- Broadcom BCM57504 Ethernet 10/25Gb 4-port SFP28 Adapter for HPE
- HPE SN1100Q 16Gb Dual Port Fibre Channel Host Bus Adapter
- HPE SN1610Q 32Gb 1-port Fibre Channel Host Bus Adapter
- HPE 7.68TB SATA RI SFF BC MV SSD
- HPE Bezel Lock Kit
- HPE C13 – C14 WW 250V 10Amp Flint Gray 2.0m Jumper Cord
- HPE 480GB SATA 6G Read Intensive SFF BC Multi Vendor SSD
- HPE ProLiant DL38x 8SFF SAS/SATA Tri-Mode Cable Kit
- HPE Smart Storage Hybrid Capacitor with 145mm Cable Kit
- RH HA 2 Sckt/2 Gst 5yr E-LTU
- Red Hat Enterprise Linux for SAP for Virtual Datacenters 3yr Subscription 24×7 Support E-LTU
- HPE ProLiant DL38x Gen10 Plus 4LFF SAS/SATA Tri-Mode Cable Kit
- RHEL Svr 2 Sckt 4 Gst 3yr 9×5 E-LTU
- Red Hat Enterprise Linux Server 2 Sockets or 2 Guests 3 Year Subscription 9×5 Support E-LTU
- HPE NS204i-p x2 Lanes NVMe PCIe3 x8 OS Boot Device
- HPE DL380 SFF Smart Array HBA H200/P400 Series SAS Cable Kit
- HPE 480GB SATA 6G Mixed Use SFF BC Multi Vendor SSD
- HPE ProLiant DL380 Gen10 Plus High Performance Heat Sink Kit
- HPE DL38X Gen10 Plus AROC to NVMe Adapter Kit
- HPE 16GB (1x16GB) Dual Rank x8 DDR4-3200 CAS-22-22-22 Registered Smart Memory Kit
- HPE C13 – C14 WW 250V 10Amp 2.0m Jumper Cord
- RHEL Svr 2 Sckt 4 Gst 5yr 9×5 E-LTU
- SLE LP 1-2 Sckt for SAP 1yr E-LTU
- HPE SN1100Q 16Gb Single Port Fibre Channel Host Bus Adapter
- HPE DDR4 DIMM Blank Kit
- Red Hat Enterprise Linux for SAP (Physical/Virtual Nodes) 5yr Subscription 24×7 Support E-LTU
- HPE BladeSystem c-Class Virtual Connect 1G SFP SX Transceiver
- Red Hat Enterprise Linux Server 2 Sockets 1 Guest 1 Year Subscription 9×5 Support E-LTU
- HPE 5 Year Tech Care Essential Proliant DL380 Gen10+ Service
- BCM 57414 10/25GbE 2p SFP28 Adptr
- RHEL Svr 2 Sckt 4 Gst 1yr 9×5 E-LTU
- RH RS 2 Sckt Unltd Gst 3yr E-LTU
- MS WS25 RDS 5USR CAL WW LTU
- Red Hat Enterprise Linux for SAP (Physical/Virtual Nodes) 5yr Subscription 9×5 Support E-LTU
- HP OV 3yr 24×7 Supp Flex E-LTU
- HPE 100Gb QSFP28 MPO SR4 100m Transceiver
- MS WS25 2C Std Add Lic WW SW
- Red Hat Enterprise Linux Server 2 Sockets or 2 Guests 1 Year Subscription 9×5 Support E-LTU
- HPE SN1200E 16Gb Dual Port Fibre Channel Host Bus Adapter
- HPE 100GbE QSFP28 SR4 100m Transceiver
- HPE SN1610Q 32Gb 2-port Fibre Channel Host Bus Adapter
- HPE 3.84TB SATA 6G Read Intensive SFF BC Multi Vendor SSD
- MS WS25 4C Std Add Lic WW SW
- HPE InfiniBand HDR100/Ethernet 100Gb 2-port QSFP56 PCIe4 x16 MCX653106A-ECAT Adapter
- Red Hat Enterprise Linux for Virtual Datacenters 2 Sockets 5 Year Subscription 24×7 Support E-LTU
- HPE 1.92TB SATA 6G Mixed Use SFF BC Multi Vendor SSD
- Broadcom BCM5719 Ethernet 1Gb 4-port BASE-T Adapter for HPE
- HPE DL38X Gen10 Plus x8/x8 Tertiary Riser Kit
- Red Hat Enterprise Linux for SAP (Physical/Virtual Nodes) 3yr Subscription 24×7 Support E-LTU
- SUSE Linux Enterprise Server SAP 1-2 Sockets or 1-2 VM 3 Year Subscription 24×7 Support E-LTU
- HPE 96W Smart Storage Lithium-ion Battery with 145mm Cable Kit
- HPE SN1200E 16Gb Single Port Fibre Channel Host Bus Adapter
- HPE 1.92TB SATA 6G Read Intensive SFF BC Multi Vendor SSD
- MS WS25 1DEV CAL WW LTU
- HPE 800W Flex Slot -48VDC Hot Plug Low Halogen Power Supply Kit
- Red Hat High Availability 2 Sockets or 2 Guests 1 Year Subscription E-LTU
- HPE 64GB 2Rx4 PC4-3200AA-R Smart Kit
- HPE BladeSystem c-Class 10Gb SFP+ SR Transceiver
- HPE Smart Array E208i-p SR Gen10 (8 Internal Lanes/No Cache) 12G SAS PCIe Plug-in Controller
- HPE 960GB SATA 6G Mixed Use SFF BC Multi Vendor SSD
- HPE Gen10 2U Bezel Kit
- HPE Trusted Platform Module 2.0 Gen10 Plus Black Rivets Kit
- HPE 600GB SAS 10K SFF BC MV HDD
- HPE 1.92TB NVMe RI SFF BC U.3 CM7 SSD
- HPE iLO Advanced Electronic License with 3yr Support on iLO Licensed Features
- HPE MR416i-a Gen10 Plus x16 Lanes 4GB Cache NVMe/SAS 12G Controller
- Red Hat High Availability 2 Sockets or 2 Guests 3 Year Subscription E-LTU
- RHEL Svr 2 Sckt 4 Gst 1yr 24×7 E-LTU
- HPE 1.8TB SAS 10K SFF BC 512E MV HDD
- Intel I350-T4 Ethernet 1Gb 4-port BASE-T Adapter for HPE
- HPE Proliant DL/ML Startup Service
- RHEL Svr 2 Sckt 1 Gst 1yr 24×7 E-LTU
- HPE Proliant DL/ML Install Service
- HPE 32GB (1x32GB) Dual Rank x4 DDR4-3200 CAS-22-22-22 Registered Smart Memory Kit
- HPE 9.5mm SATA DVD-RW Optical Drive
- HPE 1000W Flex Slot Titanium Hot Plug Power Supply Kit
- HPE Smart Array E208e-p SR Gen10 (8 External Lanes/No Cache) 12G SAS PCIe Plug-in Controller
- HPE 1600W Flex Slot Platinum Hot Plug Low Halogen Power Supply Kit
- HPE DL300 GEN10+ 2U 8SFF X1TMODE U.3 KIT
- Broadcom BCM5719 Ethernet 1Gb 4-port BASE-T OCP3 Adapter for HPE
- HPE 1.92TB NVMe Gen4 High Performance Read Intensive SFF BC U.3 PM1733a SSD
- MLX MCX631102 10/25GBE 2P SFP28 ADPTR
- Red Hat Enterprise Linux for Virtual Datacenters 2 Sockets 5 Year Subscription 9×5 Support E-LTU
- HPE BladeSystem c-Class 10Gb SFP+ LR Transceiver
- HPE 800W Flex Slot Titanium Hot Plug Low Halogen Power Supply Kit
- Red Hat Enterprise Linux for Virtual Datacenters 2 Sockets 3 Year Subscription 24×7 Support E-LTU
- SUSE Linux Enterprise High Availability Extension 1-2 Sockets 3 Year Subscription E-LTU
- Red Hat Resilient Storage 2 Sockets or 2 Guests 3 Year Subscription E-LTU
- RHEL Svr 2 Sckt 4 Gst 3yr 24×7 E-LTU
- HPE 960GB SATA 6G Read Intensive SFF BC Multi Vendor SSD
- HPE DL38X Gen10 Plus 2U SFF Easy Install Rail Kit
- HPE DL38X Gen10 Plus Maximum Performance Fan Kit
- Red Hat Enterprise Linux Server 2 Sockets or 2 Guests 1 Year Subscription 24×7 Support E-LTU
- HPE ProLiant DL380 Gen10 Plus Standard Heat Sink Kit
- RH HA 2 Sckt Unltd Gst 1yr E-LTU
- Red Hat Enterprise Linux Server 2 Sockets or Guests 5 Year Subscription 9×5 Support E-LTU
- Mellanox MCX562A-ACAI Ethernet 10/25Gb 2-port SFP28 OCP3 Adapter for HPE
- HPE 960GB SAS 12G Mixed Use SFF BC Value SAS Multi Vendor SSD
- RH RS 2 Sckt Unltd Gst 1yr E-LTU
- HPE 48VDC 2.85m Power Cable
- HPE Smart Array P408i-p SR Gen10 (8 Internal Lanes/2GB Cache) 12G SAS PCIe Plug-in Controller
- HPE C13 – KSC- 8305 KR 250V 10Amp 1.83m Power Cord
- Red Hat Enterprise Linux for SAP for Virtual Datacenters 5yr Subscription 9×5 Support E-LTU
- HPE iLO Advanced 1-server License with 3yr Support on iLO Licensed Features
- HPE SN1610E 32GB 2P FC HBA
- Red Hat Enterprise Linux Server 2 Sockets or 2 Guests 3 Year Subscription 24×7 Support E-LTU
- HPE DL38X Gen10+ 2LFF Tertiary FIO Kit
- Red Hat Enterprise Linux for Virtual Datacenters 2 Sockets 1 Year Subscription 9×5 Support E-LTU
- RH HA 2 Sckt Unltd Gst 3yr E-LTU
- MS WS25 4C DC Add Lic WW SW
- Red Hat Resilient Storage 2 Sockets Unlimited Guests 5yr Subscription E-LTU
- HPE DL38X Gen10 Plus Primary NEBS-compliant Riser Kit
- HPE InfiniBand HDR100/Ethernet 100Gb 1-port QSFP56 PCIe4 x16 MCX653105A-ECAT Adapter
- HPE Mobile USB DVD-RW Optical Drive
- HPE 1.6TB NVMe Gen4 High Performance Mixed Use SFF BC U.3 PM1735a SSD
- HPE DL38X Gen10 Plus 2U Cable Management Arm for Rail Kit
- HPE DL38X Gen10 Plus 2U LFF Easy Install Rail Kit
- HPE 5 Year Tech Care Basic Proliant DL380 Gen10+ Service
- RH HA 2 Sckt Unltd Gst 5yr E-LTU
- HPE iLO Advanced 1-server License with 1yr Support on iLO Licensed Features
- HPE 3 Year Tech Care Essential Proliant DL380 Gen10+ Service
- Broadcom BCM57416 Ethernet 10Gb 2-port BASE-T OCP3 Adapter for HPE
- Red Hat Enterprise Linux for SAP (Physical/Virtual Nodes) 3yr Subscription 9×5 Support E-LTU
- Broadcom BCM57416 Ethernet 10Gb 2-port BASE-T Adapter for HPE
- HPE Smart Array E208i-a SR Gen10 Ctrlr
- HPE Smart Array P408e-p SR Gen10 (8 External Lanes/4GB Cache) 12G SAS PCIe Plug-in Controller
- BCM 57412 10GBE 2P SFP+ OCP3 ADPTR
- SUSE Linux Enterprise Server SAP 1-2 Sockets or 1-2 VM 5 Year Subscription 24×7 Support E-LTU
- SLE LP 1-2 Sckt for SAP 3yr E-LTU
- HPE C13 – CEE-VII EU 250V 10Amp 1.83m Power Cord
- Broadcom BCM57412 Ethernet 10Gb 2-port SFP+ Adapter for HPE
- HPE ProLiant DL38x LFF SAS/SATA Tri-Mode Cable Kit
- MS WS25 10USR CAL WW LTU
- HPE 32GB microSD RAID 1 USB Boot Drive
- Red Hat Enterprise Linux for SAP for Virtual Datacenters 3yr Subscription 9×5 Support E-LTU
- HPE OV for DL 3y 24×7 Bdl Track 1Svr Lic
- HPE DL38X Gen10 Plus x16/x16 Slot 1/2 Secondary Riser Kit
- HPE 240GB SATA 6G Read Intensive SFF BC Multi Vendor SSD
- Red Hat Enterprise Linux for Virtual Datacenters 2 Sockets 1 Year Subscription 24×7 Support E-LTU
- HPE 3.84TB SAS RI SFF BC VS MV SSD
- HPE 1.83m 10A C13-UL Dom Pwr Cord
- Pensando Distributed Services Platform DSC-25 Enterprise 10/25Gb 2-port SFP28 Card
- RH RS 2 Sckt/2 Gst 5yr E-LTU
- HPE iLO Advanced Electronic License with 1yr Support on iLO Licensed Features
- HPE ProLiant DL300 Gen10 Plus 2U Standard Fan Kit
- HPE 7.68TB SAS 12G Read Intensive SFF BC Value SAS Multi Vendor SSD
- HPE 25Gb SFP28 SR 100m Transceiver
- Intel I350-T4 Ethernet 1Gb 4-port BASE-T OCP3 Adapter for HPE
- Red Hat Enterprise Linux for Virtual Datacenters 2 Sockets 3 Year Subscription 9×5 Support E-LTU
- HPE 1.2TB SAS 12G Mission Critical 10K SFF BC 3-year Warranty Multi Vendor HDD
- HPE InfiniBand HDR/Ethernet 200Gb 1-port QSFP56 PCIe4 x16 MCX653105A-HDAT Adapter
- HPE DL38X Gen10 Plus x16 Tertiary Riser Kit
- HPE 9.5mm SATA DVD-ROM Jb Gen9 Kit
Documents
- HPE Reference Configuration for Red Hat OpenShift Virtualization on HPE ProLiant DL360 and DL380 Gen11 servers using Red Hat OpenShift Container Platform 4.15
- HPE Firmware and Software Compatibility Matrix for VMware Cloud Foundation 4.3.1 on HPE Synergy and HPE ProLiant Servers Dec2021
- 360-Degree Security where and when you need it
- HPE ProLiant DL380 Gen10 Plus Server QuickSpecs
- HPE Server Performance Benchmarks Newsletter
- Iceotope Develops Innovative Cooling Systems for Extreme Environments
- Upgrading VMware Cloud Foundation from 4.0.1 to 4.2.1 on HPE Servers
- HPE ProLiant DL360 Gen10 Plus and HPE ProLiant DL380 Gen10 Plus Servers Building Blocks for SAP Implementation
- Expanding patient services, reducing wait times – PrairieStar Health Center
- Expanding patient services, reducing wait times – PrairieStar Health Center
- How To Choose The Right AI Tools To Create Value
- Next-Gen Data Backup Drives Secure, Scalable, Manageable IT
- HPE ProLiant DL380 Gen10 Plus – Carrier Grade Supplement QuickSpecs
- HPE and Bloombase – HPE ProLiant and Bloombase StoreSafe Intelligent Storage Firewall
- HPE and F5 – HPE ProLiant and F5 BIG-IP ADC and F5 Distributed Cloud Platform
- Expanding patient services, reducing wait times – PrairieStar Health Center
- Azure Stack HCI – Secured-Core Server solution overview
- HPE ProLiant Compute DL380a Gen12
- Verified Reference Configuration – Intel-HPE VRC for NFVI and SASE
HDD Seagate IronWolf Pro 6TB SATA-III 7200RPM 256MB (ST6000NT001) 




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